Source: | Rabbit | Gene Id: | 5300 |
Isotype: | IgG | Swiss Prot: | Q13526 |
purity: | Affinity purification |
Background: |
Pin1, a member of the parvulin family of peptidyl-prolyl isomerases (PPIase), has been implicated in the G2/M transition of the mammalian cell cycle (1-6). Pin1 is a small (18 kDa) protein with two distinct functional domains: an amino-terminal WW domain and a carboxy-terminal PPlase domain. Pin1 interacts with several mitotic phosphoproteins, including Plk1, cdc25C and cdc27, and is thought to act as a phosphorylation-dependent PPlase for these target molecules (7-9). |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 18 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:200
|
Immunogen | Recombinant protein of human PIN1 |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | DOD, UBL5 |
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