
| Source: | Rabbit | Gene Id: | 5300 | 
| Isotype: | IgG | Swiss Prot: | Q13526 | 
| purity: | Affinity purification | 
| Background: | 
| Pin1, a member of the parvulin family of peptidyl-prolyl isomerases (PPIase), has been implicated in the G2/M transition of the mammalian cell cycle (1-6). Pin1 is a small (18 kDa) protein with two distinct functional domains: an amino-terminal WW domain and a carboxy-terminal PPlase domain. Pin1 interacts with several mitotic phosphoproteins, including Plk1, cdc25C and cdc27, and is thought to act as a phosphorylation-dependent PPlase for these target molecules (7-9). | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 18 kDa | 
| Recommended Dilutions | WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 | 
| Immunogen | Recombinant protein of human PIN1 | 
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Synonym | DOD, UBL5 | 
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