PGC Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5225-01 50ul 1500.00 In Stock
ARP5225-01 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Rabbit Gene Id: 5225
Isotype: IgG Swiss Prot: P20142
purity: Affinity purification
Background:
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 42 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:100
Immunogen Synthetic Peptide of human PGC
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym PEPC, PGII
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us