Source: | Rabbit | Gene Id: | 50855 |
Isotype: | IgG | Swiss Prot: | Q9NPB6 |
purity: | Affinity purification |
Background: |
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Reactivity | Human |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 37 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
|
Immunogen | Synthetic Peptide of human PARD6A |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | PAR6, PAR6C, TAX40, PAR-6A, TIP-40, PAR6alpha |
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