MMP8 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP4317-01 50ul 1500.00 In Stock
ARP4317-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 4317
Isotype: IgG Swiss Prot: P22894
purity: Affinity purification
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Reactivity Human, Mouse
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 53 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:100
Immunogen Synthetic Peptide of human MMP8
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym HNC, CLG1, MMP-8, PMNL-CL
This product is for research use only, not for diagnostic or therapeutic use!

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