| No | Size | Price | Availability | |
| ARP4092-01 | 50ul | 1500.00 | In Stock |  |
| ARP4092-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4092 |
| Isotype: | IgG | Swiss Prot: | O15105 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 46 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
IF 1:20-1:50
|
| Immunogen | Recombinant protein of human SMAD7 |
| Storage | Store at 4°C (regular) or -20°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym |
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