IFNA1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP3439-01 50ul 1500.00 In Stock
ARP3439-01 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Rabbit Gene Id: 3439
Isotype: IgG Swiss Prot: P01562
purity: Affinity purification
Background:
Interferon-α1 is a member of the Type I IFN (1) family best known for their antiviral activity. Most nucleated cells produce one or more Type I IFNs in response to viral infection (2). Secreted Type I IFN then induces viral protective responses in neighboring non-infected cells. Type I IFNs also enhance virus-induced apoptosis (3). Other IFNA11 activities include enhancement of dendritic cell maturation and cytotoxic T cell activity (4). IFNA11 binds to the IFNA1R1 and IFNA1R2 heterodimer (1). Intracellular signaling through the Jak/Stat pathway is best characterized (3). However, the PI3K, ERK, and p38 kinase pathways are also involved (5). The antiviral activities of the IFNs have led to their use in treating viral infections (4). Type I IFNs also appear to have an integral role in several autoimmune diseases (6).
Reactivity Human, Mouse
Tested applications WB IF
Clonality Polyclonal Antibody
Calculated MW 22 kDa
Recommended Dilutions
WB 1:500-1:2000
IF 1:100-1:200
Immunogen Recombinant protein of human IFNA1
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym IFL, IFN, IFNA@, IFNA13, IFN-ALPHA, IFN-alphaD
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us