| Source: | Rabbit | Gene Id: | 203523 | 
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. | 
| Background: | 
| Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr??ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF449 is a 518 amino acid protein that contains one SCAN box domain and seven C2H2-type zinc fingers. ZNF449 is ubiquitously expressed and localizes to the nucleus. There are three isoforms of ZNF449 that are produced as a result of alternative splicing events. | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                     WB 1:100-1:1000 
                                    IHC 1:100-1:500 
                                    IF 1:50-1:200 
                                    
                                    
                                    
                                    
                                 | 
                            
| Immunogen | KLH conjugated synthetic peptide derived from human ZNF449 | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | FLJ23614, OTTHUMP00000024072, Zinc finger and SCAN domain containing protein 19, Zinc finger and SCAN domain-containing protein 19, Zinc finger protein 449, ZN449_HUMAN, ZNF449, ZSCAN19. | 
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