| No | Size | Price | Availability | |
| ARP29072-01 | 50ul | 1500.00 | In Stock |  |
| ARP29072-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 29072 |
| Isotype: | IgG | Swiss Prot: | Q9BYW2 |
| purity: | Affinity purification |
| Background: |
| Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF IP ChIP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 287 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:200
|
| Immunogen | Recombinant protein of human SETD2 |
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP |
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