Phospho-ALK-Y1096 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP238P-01 50ul 1500.00 In Stock
ARP238P-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 238
Isotype: IgG Swiss Prot: Q9UM73
purity: Affinity purification
Background:
This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011]
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 176 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Synthetic Peptide of human Phospho-ALK-Y1096
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym CD246, NBLST3
This product is for research use only, not for diagnostic or therapeutic use!

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