| No | Size | Price | Availability | |
| ARP203068-01 | 50ul | 1500.00 | In Stock |  |
| ARP203068-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 203068 |
| Isotype: | IgG | Swiss Prot: | P07437 |
| purity: | Affinity purification |
| Background: |
| Microtubules are essential parts in eukaryotic cell structures, transportation, and mitosis and consists mainly of 2 soluble protein subunits, alpha and beta tubulin. Beta-tubulin binds to alpha tubulin to form tubulin heterodimer which is post-translationally modified. The tubulin dimer complex binds to GTP and assembles onto the positive ends of microtubules. After incorporation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule incorporation. Mutation on beta-tubulin has been linked to anti-cancer drug resistance in lung cancers. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | Recombinant protein of human TUBB |
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | M40, TUBB1, TUBB5, CDCBM6, OK/SW-cl.56 |
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