
| Source: | Rabbit | Gene Id: | 1910 | 
| Isotype: | IgG | Swiss Prot: | P24530 | 
| purity: | Affinity purification | 
| Background: | 
| The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | 
| Reactivity | Human, Mouse | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 50 kDa | 
| Recommended Dilutions | WB 1:500-1:2000 IHC 1:50-1:100 | 
| Immunogen | Synthetic Peptide of human EDNRB | 
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Synonym | ETB, ET-B, ETBR, ETRB, HSCR, WS4A, ABCDS, ET-BR, HSCR2 | 
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