
| Source: | Rabbit | Gene Id: | 23090 | 
| Isotype: | IgG | Swiss Prot: | Q2M1K9 | 
| purity: | Purified by Protein A. | 
| Background: | 
| Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation. | 
| Reactivity | Mouse, Rat | 
| Tested applications | WB IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                     WB 1:100-1:1000 
                                    IHC 1:100-1:500 
                                    IF 1:50-1:200 
                                    
                                    
                                    
                                    
                                 | 
                            
| Immunogen | KLH conjugated synthetic peptide derived from human ZNF423/OAZ | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | OAZ, Roaz, hOAZ, Ebfaz, JBTS19, NPHP14, ZFP423, Zfp104, Zinc finger protein 423, Olf1/EBF-associated zinc finger protein, Smad- and Olf-interacting zinc finger protein, ZNF423, KIAA0760 | 
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.