Source: | Rabbit | Gene Id: | 1759 |
Isotype: | IgG | Swiss Prot: | Q05193 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. |
Reactivity | Human, Mouse |
Tested applications | WB IF |
Clonality | Polyclonal Antibody |
Calculated MW | 98 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:100-1:200
|
Immunogen | Synthetic Peptide of human DNM1 |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | DNM |
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