AANAT Rabbit Polyclonal Antibody
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ARP15-01 50ul 1500.00 In Stock
ARP15-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 15
Isotype: IgG Swiss Prot: Q16613
purity: Affinity purification
Background:
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Reactivity Human
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 23 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen Recombinant protein of human AANAT
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym DSPS, SNAT
This product is for research use only, not for diagnostic or therapeutic use!

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