FBXO32 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP114907-01 50ul 1500.00 In Stock
ARP114907-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 114907
Isotype: IgG Swiss Prot: Q498Y9
purity: Affinity purification
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 41 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Recombinant protein of human FBXO32
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym Fbx32, MAFbx
This product is for research use only, not for diagnostic or therapeutic use!

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