Source: | Rabbit | Gene Id: | 1073 |
Isotype: | IgG | Swiss Prot: | Q9Y281 |
purity: | Affinity purification |
Background: |
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IF |
Clonality | Polyclonal Antibody |
Calculated MW | 19 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:50-1:100
|
Immunogen | Recombinant protein of human CFL2 |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | NEM7 |
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