Source: | Rabbit | Gene Id: | 10393 |
Isotype: | IgG | Swiss Prot: | Q9UM13 |
purity: | Affinity purification |
Background: |
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011] |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 21 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | Recombinant protein of human ANAPC10 |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym |
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