| No | Size | Price | Availability | |
| ARP100507436-01 | 50ul | 1500.00 | In Stock |  |
| ARP100507436-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 100507436 |
| Isotype: | IgG | Swiss Prot: | Q29983 |
| purity: | Affinity purification |
| Background: |
| MICA and MICB are stress-induced antigens that are related to major histocompatibility complex (MHC) class I molecules. MICA and MICB are frequently expressed in epithelial tumors. These highly glycosylated cell surface proteins are stably expressed without conventional class I peptide ligands or association with b-2-Microglobulin. The expression is induced on proliferating or heat shock-stressed epithelial cells. MICA and MICB are broadly recognized by intestinal epithelial Vd1 gd T cells expressing variable TCRs, suggesting that these antigens may play a central role in the signaling of cellular distress to evoke immune responses in the intestinal epithelium. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 43 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | Recombinant protein of human MICA |
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | MIC-A, PERB11.1 |
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