| No | Size | Price | Availability | |
| ARP10891-51 | 50ul | 1500.00 | In Stock |  |
| ARP10891-51 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10891 |
| Isotype: | IgG | Swiss Prot: | Q9UBK2 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. |
| Reactivity | Chicken, Cow, Dog, Horse, Human, Mouse, Pig, Rat |
| Tested applications | WB ELISA IP IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 90 kDa |
| Recommended Dilutions |
WB 1:100-1:1000
IF 1:50-1:500
|
| Immunogen | A synthetic peptide corresponding to amino acids 1-300 mapping at the N-terminus of human PPARGC1A |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | LEM6, PGC1, PGC1A, PGC-1v, PPARGC1, PGC-1(alpha) |
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