Source: | Rabbit | Gene Id: | 64581 |
Isotype: | IgG | Swiss Prot: | Q9BXN2 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC ELISA IP IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 28 kDa |
Recommended Dilutions |
WB 1:100-1:500
IHC 1:100-1:500
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide corresponding to residues surrounding amino acids 161 of human CLEC7A |
Storage | Store at -20°C. For long term storage store at -80°C in PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal).Avoid freeze/thaw cycles. |
Synonym | BGR, CLECSF12, DECTIN1 |
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