| No | Size | Price | Availability | |
| ARP1277-31 | 50ul | 1500.00 | In Stock |  |
| ARP1277-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1277 |
| Isotype: | IgG | Swiss Prot: | P02452 |
| purity: | Affinity purification |
| Background: |
| Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 180 kDa |
| Recommended Dilutions |
WB 1:100-1:400
IHC 1:50-1:200
ICC 1:100-1:500
|
| Immunogen | A recombinant protein of human COL1A1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | OI4 |
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