Source: | Rabbit | Gene Id: | 2903 |
Isotype: | IgG | Swiss Prot: | Q12879 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. |
Reactivity | Human, Mouse, Rabbit, Rat |
Tested applications | WB IHC ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 165 kDa |
Recommended Dilutions |
WB 1:100-1:400
IHC 1:50-1:200
ICC 1:100-1:500
|
Immunogen | A synthetic peptide of human GRIN2A |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | LKS, EPND, FESD, NR2A, GluN2A, NMDAR2A |
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