Phospho-HIST1H3A-Ser10 Rabbit Polyclonal Antibody (Alexa Fluor(R) 488 Conjugate)
No Size Price Availability  
ARP8350P-21C 50ul 1500.00 In Stock
ARP8350P-21C 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 8350
Isotype: / Swiss Prot: P68431
purity: Affinity purification
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq
Reactivity D. melanogaster, Human, Monkey, Mouse, Rat, Zebrafish, S. cerevisiae
Tested applications FC
Clonality Polyclonal Antibody
Calculated MW 17 kDa
Recommended Dilutions
FC 1:50
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser10 of human histone H3 The antibody was conjugated to Alexa Fluor®488 under optimal conditions with an F/P ratio of 2-6
Storage Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Synonym H3.4, H3/g, H3FT, H3t, MGC126886, MGC126888
This product is for research use only, not for diagnostic or therapeutic use!

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