Source: | Rabbit | Gene Id: | 7293 |
Isotype: | IgG | Swiss Prot: | P43489 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 29 kDa |
Recommended Dilutions |
WB 1:100-1:400
|
Immunogen | A synthetic peptide of human TNFRSF4 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | OX40, ACT35, CD134, TXGP1L |
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