| No | Size | Price | Availability | |
| ARPF047P-23 | 50ul | 1500.00 | In Stock |  |
| ARPF047P-23 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6195/6196/6197 |
| Isotype: | / | Swiss Prot: | Q15418/P51812/Q15349 |
| purity: | Affinity purification |
| Background: |
| The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains (1) and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs) (2). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation (3). RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters (3). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 90 kDa |
| Recommended Dilutions |
WB 1:1000
IF 1:400
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr573 of human p90RSK |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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