| No | Size | Price | Availability | |
| ARP7297P-21 | 50ul | 1500.00 | In Stock |  |
| ARP7297P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7297 |
| Isotype: | / | Swiss Prot: | P29597 |
| purity: | Affinity purification |
| Background: |
| Tyk2, a member of the Jak family of protein tyrosine kinases, associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and interferon-alpha and beta (1-3). Following ligand binding, Tyk2 is activated by phosphorylation on Tyr1054 and/or Tyr1055 (4). Tyk2 is required for the tyrosine phosphorylation of Stat3 in the IFN-beta signaling cascade (5). |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 134 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Tyr1054/1055 of human Tyk2 protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | JTK1 |
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