| Source: | Rabbit | Gene Id: | 1386 |
| Isotype: | / | Swiss Prot: | P15336 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq |
| Reactivity | Human, Monkey, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 70 kDa |
| Recommended Dilutions |
WB 1:1000
IHC 1:100
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr69 and Thr71 of human ATF-2 |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CRE-BP1, CREB2, HB16, MGC111558, TREB7 |
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