Source: | Rabbit | Gene Id: | 1386 |
Isotype: | / | Swiss Prot: | P15336 |
purity: | Affinity purification |
Background: |
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 70 kDa |
Recommended Dilutions |
WB 1:1000
IHC 1:100
|
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr69 and Thr71 of human ATF-2 |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CRE-BP1, CREB2, HB16, MGC111558, TREB7 |
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