Source: | Rabbit | Gene Id: | 66141(Mouse) |
Isotype: | / | Swiss Prot: | Q9CQW9 |
purity: | Affinity purification |
Background: |
Fragilis (Ifitm3) belongs to the interferon (IFN)-inducible transmembrane protein family (1), which consists of five highly similar transmembrane proteins that are conserved among mammalian species (2). It is thought to be the first gene to mark the onset of germ cell competence during embryonic development in mice (3). Cells expressing high levels of fragilis protein go on to express stella, a protein found exclusively in lineage-restricted germ cells (3). Studies on fragilis family members could help elucidate the mechanisms through which interferons act as signaling molecules during embryonic development (2). |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IP |
Clonality | Polyclonal Antibody |
Calculated MW | 12 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic peptide corresponding to residues surrounding Gln16 of mouse fragilis protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | / |
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