| Source: | Rabbit | Gene Id: | 56852 | 
| Isotype: | / | Swiss Prot: | Q9NS91 | 
| purity: | Affinity purification | 
| Background: | 
| The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. | 
| Reactivity | Human | 
| Tested applications | WB IP | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 80, 90 kDa | 
| Recommended Dilutions | WB 1:1000 | 
| Immunogen | A synthetic peptide corresponding to residues surrounding Ser403 of human Rad18 protein | 
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | RNF73 | 
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