Cre Recombinase Rabbit Polyclonal Antibody
No Size Price Availability  
PRP277747-21 50ul 1500.00 In Stock
PRP277747-21 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 2777477(Phage)
Isotype: / Swiss Prot: P06956
purity: Affinity purification
Background:
Cre recombinase is a bacteriophage-P1 enzyme required for maintenance of the phage genome as a monomeric plasmid in the lysogenic state (1,2). This enzyme mediates a site-specific recombination between two 34 base pair loxP sites. This reaction can be carried out in vitro, indicating that it does not require accessory factors (3). The Cre/Lox system has been used for a number of in vitro and in vivo applications including targeted gene deletions (4) and gene-specific humanized animal models (5). Resolution of the crystal structure of the Cre-Lox complex revealed that two Cre molecules interact with a single Lox site (6).
Reactivity All
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 38 kDa
Recommended Dilutions
WB 1:1000
Immunogen A synthetic peptide corresponding to residues surrounding Asp141 of Cre recombinase protein
Storage Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Synonym P1_gp003
This product is for research use only, not for diagnostic or therapeutic use!

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