Source: | Rabbit | Gene Id: | 7249 |
Isotype: | / | Swiss Prot: | P49815 |
purity: | Affinity purification |
Background: |
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | WB IP |
Clonality | Polyclonal Antibody |
Calculated MW | 200 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser1387 of human tuberin protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | FLJ43106, LAM, TSC4 |
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