| No | Size | Price | Availability | |
| ARP51496P-21 | 50ul | 1500.00 | In Stock |  |
| ARP51496P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 51496 |
| Isotype: | / | Swiss Prot: | Q05D32 |
| purity: | Affinity purification |
| Background: |
| CTD small phosphatase-like protein 2 (CTDSPL2, HSPC129) is a putative RNA-polymerase II carboxy-terminal domain (CTD) phosphatase (1) that belongs to a small subfamily of CTD phosphatases (2). The CTD of RNA polymerase II contains multiple Y-S-P-T-S-P-S repeats that are phosphorylated during the transcription cycle (3,4). In general, CTD phosphatases regulate the reversible CTD phosphorylation state of RNA-polymerase II at several stages of RNA synthesis and during post-transcriptional modification (4-6). CTDSPL2 has several structural and functional similarities to other CTD phosphatases, including FCP1, SCP1, DULLARD, and UBLCP1 (1,2). |
| Reactivity | Human, Monkey |
| Tested applications | WB IP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 61 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser104 of human CTDSPL2 protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | FLJ10523, HSPC058, HSPC129 |
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