| No | Size | Price | Availability | |
| ARP6833-31 | 50ul | 1500.00 | In Stock |  |
| ARP6833-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6833 |
| Isotype: | IgG | Swiss Prot: | Q09428 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. |
| Reactivity | Human, Mouse, Rat, Dog, Pig, Horse, Guinea pig |
| Tested applications | WB IHC ELISA IP IF FC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 175 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:100-1:500
IF 1:100-1:500
FC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human ABCC8 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | HI, SUR, HHF1, MRP8, PHHI, SUR1, ABC36, HRINS, TNDM2, SUR1delta2 |
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