| No | Size | Price | Availability | |
| ARP9531-31 | 50ul | 1500.00 | In Stock |  |
| ARP9531-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9531 |
| Isotype: | IgG | Swiss Prot: | O95817 |
| purity: | Affinity purification |
| Background: |
| BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
| Reactivity | Chicken, Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep |
| Tested applications | WB IHC ELISA IP IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 61 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:100-1:500
IF 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human BAG3 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BIS, MFM6, BAG-3, CAIR-1 |
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