| No | Size | Price | Availability | |
| ARP2997P-21 | 50ul | 1500.00 | In Stock |  |
| ARP2997P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2997 |
| Isotype: | / | Swiss Prot: | P13807 |
| purity: | Affinity purification |
| Background: |
| Glycogen synthase (GS) is a key enzyme in the regulation of glycogen synthesis. There are two main isoforms of mammalian GS: the muscle and the liver isoform (1-2). Muscle GS is expressed in several tissues, and liver GS appears to be tissue specific (3). GS is regulated by multi-site phosphorylation and by the binding of allosteric ligands. Phosphorylation leads to inactivation of GS, but activity is restored by the binding of the allosteric activator glucose-6-phosphate, which induces its dephosphorylation and activation (4).Ser641 is one of the most important phosphorylation sites for the regulation of glycogen synthase (5). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 85 to 90 kDa |
| Recommended Dilutions |
WB 1:1000
IHC 1:50
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser641 of human liver glycogen synthase |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | GSY, GYS |
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