| No | Size | Price | Availability | |
| ARP1581-31 | 50ul | 1500.00 | In Stock |  |
| ARP1581-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1581 |
| Isotype: | IgG | Swiss Prot: | P22680 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. |
| Reactivity | Guinea pig, Human, Mouse, Pig, Rat, Rabbit |
| Tested applications | WB IHC ELISA IP IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 55 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:100-1:500
IF 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human CYP7A1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CP7A, CYP7, CYPVII |
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