| No | Size | Price | Availability | |
| ARP29102-21 | 50ul | 1500.00 | In Stock |  |
| ARP29102-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 29102 |
| Isotype: | IgG | Swiss Prot: | Q9NRR4 |
| purity: | Affinity purification |
| Background: |
| Drosha was identified as a nuclear RNase III that catalyzes the initial step of microRNA (miRNA) processing (1). This enzyme processes the long primary transcript pri-miRNAs into stem-looped pre-miRNAs. Interference of Drosha results in the increase of pri-miRNAs and the decrease of pre-miRNAs (1). Drosha exists in a multiprotein complex called Microprocessor along with other components such as DGCR8 (2). Drosha, along with DGCR8, is necessary for miRNA biogenesis (3). |
| Reactivity | Human, Mouse |
| Tested applications | WB IP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 160 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic peptide corresponding to residues surrounding Gly953 of human Drosha |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DROSHA, ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L |
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