| Source: | Rabbit | Gene Id: | 182 |
| Isotype: | IgG | Swiss Prot: | P78504 |
| purity: | Affinity purification |
| Background: |
| The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC ELISA IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 134 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:100-1:500
IF 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human CD339 |
| Storage | Store at -20°C or in lyophilized state. Avoid freeze/thaw cycles. |
| Synonym | AGS, AHD, AWS, HJ1, CD339, JAGL1 |
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