Source: | Rabbit | Gene Id: | 13805(Mouse) |
Isotype: | / | Swiss Prot: | Q63961 |
purity: | Affinity purification |
Background: |
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Reactivity | Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 79, 81 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic peptide corresponding to residues surrounding Pro430 of mouse endoglin |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Endo, CD105, AI528660, AI662476, S-endoglin |
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