| No | Size | Price | Availability | |
| ORP20304-21S | 50ul | 1500.00 | In Stock |  |
| ORP20304-21S | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 20304(Mouse)/81780(Rat) |
| Isotype: | / | Swiss Prot: | P30882/P50231 |
| purity: | Affinity purification |
| Background: |
| This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. |
| Reactivity | Mouse |
| Tested applications | WB IP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 10 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic peptide corresponding to residues at the carboxyl terminus of rodent RANTES |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | SISd, Scya5, RANTES, TCP228, MuRantes |
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