| No | Size | Price | Availability | |
| HRP578-21S | 50ul | 1500.00 | In Stock |  |
| HRP578-21S | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 581 |
| Isotype: | / | Swiss Prot: | Q07812 |
| purity: | Affinity purification |
| Background: |
| Bax is a key component for cellular induced apoptosis through mitochondrial stress (1). Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane (2). Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis (3,4). |
| Reactivity | Human, Monkey |
| Tested applications | WB IHC IP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 20 kDa |
| Recommended Dilutions |
WB 1:1000
IHC 1:100
|
| Immunogen | A synthetic peptide corresponding to residues surrounding lysine 58 of human Bax |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BCL2L4 |
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