| No | Size | Price | Availability | |
| ARP5499P-21 | 50ul | 1500.00 | In Stock |  |
| ARP5499P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5499 |
| Isotype: | / | Swiss Prot: | P62136 |
| purity: | Affinity purification |
| Background: |
| Type 1 protein phosphatase (PP1), a serine/threonine phosphatase, is highly conserved in eukaryotic cells. Four isoforms of PP1 have been characterized: PP1α, PP1δ, PP1γ1 and PP1γ2 (1). Involvement in cell cycle regulation is one of the biological functions of PP1 (1). It has been illustrated that PP1 dephosphorylates Rb and cdc25 during mitosis (2,3). A cell cycle-dependent phosphorylation at Thr320 of PP1α by cdc2 kinase inhibits PP1α activity (4). |
| Reactivity | Human, Monkey, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 38 kDa |
| Recommended Dilutions |
WB 1:1000
IHC 1:50
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr320 of human PP1α |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | PPP1CA, MGC15877, MGC1674, PP-1A, PP1alpha, PPP1A |
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