| No | Size | Price | Availability | |
| ARP23411P-22 | 50ul | 1500.00 | In Stock |  |
| ARP23411P-22 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 23411 |
| Isotype: | / | Swiss Prot: | Q96EB6 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB IP IF FC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 120 kDa |
| Recommended Dilutions |
WB 1:2000
IF 1:100
FC 1:100
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser47 of human SirT1 |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | SIR2L1 |
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