Source: | Rabbit | Gene Id: | 12122(Mouse) |
Isotype: | / | Swiss Prot: | P70444 |
purity: | Affinity purification |
Background: |
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq |
Reactivity | Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 22 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic peptide corresponding to residues surrounding the cleavage site of mouse BID |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | 2700049M22Rik, AI875481, AU022477 |
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