| No | Size | Price | Availability | |
| ARP780P-21 | 50ul | 1500.00 | In Stock |  |
| ARP780P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 780 |
| Isotype: | / | Swiss Prot: | Q08345 |
| purity: | Affinity purification |
| Background: |
| The discoidin domain receptors (DDRs) are receptor tyrosine kinases with a discoidin homology repeat in their extracellular domains, activated by binding to extracellular matrix collagens. So far, two mammalian DDRs have been identified: DDR1 and DDR2 (1). They are widely expressed in human tissues and may have roles in smooth muscle cell-mediated collagen remodeling (2). Research studies have implicated aberrant expression and signaling of DDRs in human diseases related to increased matrix degradation and remodeling, such as cardiovascular disease, liver fibrosis, and tumor invasion (1). |
| Reactivity | Human, (Mouse, Rat) |
| Tested applications | WB IP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 125 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Tyr792 of human DDR1 protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CAK, CD167, DDR, EDDR1, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE |
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