Source: | Rabbit | Gene Id: | 10010 |
Isotype: | / | Swiss Prot: | Q92844 |
purity: | Affinity purification |
Background: |
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IP |
Clonality | Polyclonal Antibody |
Calculated MW | 50 kDa |
Recommended Dilutions |
WB 0.5-4 ug/mL
IHC 10-20 ug/mL
|
Immunogen | A synthetic peptide corresponding to residues surrounding amino acids 413 of human TANK |
Storage | Store at -20°C. For long term storage store at -80°C in PBS (30% glycerol, 0.1% BSA, 0.01% thimerosal).Avoid freeze/thaw cycles. |
Synonym | I-TRAF, TRAF2 |
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