Source: | Rabbit | Gene Id: | 4296 |
Isotype: | / | Swiss Prot: | Q16584 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 92 kDa |
Recommended Dilutions |
WB 0.5-4 ug/mL
|
Immunogen | A synthetic peptide corresponding to C-terminus of human MAP3K11 |
Storage | Store at -20°C. For long term storage store at -80°C in PBS (50% glycerol, 1.0% BSA, 0.02% thimerosal).Avoid freeze/thaw cycles. |
Synonym | MGC17114, MLK-3, MLK3, PTK1, SPRK |
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