Source: | Rabbit | Gene Id: | 604 |
Isotype: | / | Swiss Prot: | P41182 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IP |
Clonality | Polyclonal Antibody |
Calculated MW | 87-98 kDa |
Recommended Dilutions |
WB 0.5-4 ug/mL
IHC 20-40 ug/mL
|
Immunogen | A synthetic peptide corresponding to C-terminus of human BCL6 |
Storage | Store at -20°C. For long term storage store at -80°C in PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal).Avoid freeze/thaw cycles. |
Synonym | BCL5, BCL6A, LAZ3, ZBTB27, ZNF51 |
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