| No | Size | Price | Availability | |
| ARP84962-11 | 50ul | 1500.00 | In Stock |  |
| ARP84962-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 84962 |
| Isotype: | / | Swiss Prot: | Q96IF1 |
| purity: | Affinity purification |
| Background: |
| Ajuba belongs to the Zyxin/Ajuba family, members of which include LIMD1, LPP, Trip6 and Zyxin. Three LIM domains at the carboxy-terminus characterize this family of proteins. Zyxin/Ajuba family members associate with the actin cytoskeleton, are components of both cell-cell junction adhesive complex and integrin-mediated adhesive complex, and shuttle in and out of the nucleus (1). Ajuba is involved in Rac activation during cell migration and activates Aurora A in order to commit to mitosis (2-3). Ajuba and its family members also have an amino-terminal proline-rich pre-LIM region, and Ajuba augments ERK activation in a Ras-dependent manner (4). |
| Reactivity | Human |
| Tested applications | IP ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 55 kDa |
| Recommended Dilutions |
ICC 2-5 ug/mL
|
| Immunogen | A recombinant GST fusion protein corresponding to human JUB |
| Storage | Store at -20°C in PBS (0.1% proclin, 2.0% Block Ace).Avoid freeze/thaw cycles. |
| Synonym | Ajuba, MGC15563 |
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