| No | Size | Price | Availability | |
| ARP5742-13 | 50ul | 1500.00 | In Stock |  |
| ARP5742-13 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5742 |
| Isotype: | / | Swiss Prot: | P23219 |
| purity: | Affinity purification |
| Background: |
| Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 70 kDa |
| Recommended Dilutions |
WB 2 ug/mL
IHC 1-2 ug/mL
|
| Immunogen | A synthetic peptide corresponding to amino acids at N-terminus of human PTGS1 |
| Storage | Store at -20°C on dry atmosphere. |
| Synonym | COX1, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS |
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